| Entry |
|
|---|
| Name |
Phendimetrazine (INN) |
|---|
| Formula |
C12H17NO
|
|---|
| Exact mass |
191.131
|
|---|
| Mol weight |
191.2695
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG03085 Selective norepinephrine reuptake inhibitor (NRI)
Gastrointestinal agent
DG01705 Anoretic
DG01704 Phenethylamine anorexic
|
|---|
| Remark |
| Product (DG01537): | D02080<US> |
|
|---|
| Efficacy |
Appetite suppressant (systemic), Stimulant (central) |
|---|
| Comment |
Active form of prodrug: Phenmetrazine [CPD: C07432]
Morpholine derivative
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Neuropsychiatric agent
DG03085 Selective norepinephrine reuptake inhibitor (NRI)
DG01537 Phendimetrazine
D08347 Phendimetrazine
Gastrointestinal agent
DG01705 Anoretic
DG01704 Phenethylamine anorexic
DG01537 Phendimetrazine
D08347 Phendimetrazine
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC6
SLC6A2 (NAT1)
D08347 Phendimetrazine (INN)
Narcotics and psychotropics in Japan [br08308.html]
Psychotropics by Cabinet order Article 3 (78 substances)
D08347
Drug groups [BR:br08330]
Neuropsychiatric agent
DG03085 Selective norepinephrine reuptake inhibitor (NRI)
DG01537 Phendimetrazine
Gastrointestinal agent
DG01705 Anoretic
DG01704 Phenethylamine anorexic
DG01537 Phendimetrazine
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 14
1 C8x C 15.3300 -27.5100
2 C8x C 15.3300 -28.9100
3 C8x C 16.5424 -29.6100
4 C8x C 17.7549 -28.9100
5 C8y C 17.7549 -27.5100
6 C8x C 16.5424 -26.8100
7 C1y C 18.9860 -26.7990
8 C1y C 20.1912 -27.4947
9 N1y N 21.4035 -26.7946
10 C1x C 21.4035 -25.3946
11 C1x C 20.1983 -24.6989
12 O2x O 18.9859 -25.3990
13 C1a C 22.6351 -27.5054
14 C1a C 20.1916 -28.9096
BOND 15
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 7 5 1 #Down
8 7 8 1
9 8 9 1
10 9 10 1
11 10 11 1
12 11 12 1
13 7 12 1
14 9 13 1
15 8 14 1 #Up
|
|---|
